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How high levels of uric acid in us could harm our eyesight or vision?

Posted on: 29/Oct/2025 9:45:51 AM

High levels of uric acid not only affect our joints and cause kidney stones etc but it can lead to eye issues also.  Shocking right!!

Purines are present in foods like certain legumes, red meat and seafood etc and uric acid is produced when our body breaks down purines. We can get hyperuricemia if uric acid doesn`t get excreted through urine that is when production exceeds excretion.

It is noteworthy that excess uric acid could form MSU or monosodium urate crystals and this MSU can accumulate in our joints, kidneys and ocular tissues etc. It was published in the journal National Centre for Biotechnology Information that excess uric acid could lead to ocular based complications. Therefore, it is necessary that we must keep an eye on uric acid levels for our eye health.

High uric acid levels can affect our eyes in these ways.

Causes Dry eye disease:

We can get dry eye disease if we have high uric acid levels in us. Persons with dry eyes would have insufficient tear production in their eyes. They might have symptoms like irritation, redness, burning and blurred vision etc. There are chances of getting corneal damage also if dry eyes issue persists for a long time.

Causes tophi formation:

If a person has high uric acid levels, then he or she could have deposits of monosodium urate crystals or topi on their eyelids, conjunctiva, cornea etc. In the beginning, topji might be painless but can lead to swelling, redness and issues in the vision etc. Truth is that the presence of ocular trophy indicates that the person has long term uncontrolled hyperuricemia.

Causes uveitis:

Iris, ciliary body and choroid form the uveal tract and uveitis is inflammation of this tract. Those persons with uveitis would show symptoms like eye pain, light sensitivity, blurred vision and floaters etc. It is true that if left untreated then uveitis can lead to permanent vision damage. By systemic inflammation and by oxidative stress, hyperuricemia can lead to uveitis in us.

Causes glaucoma:

Increased intraocular pressure can lead to damage of the optic nerve and this is glaucoma. It was brought out by research that high uric acid levels in us can lead to glaucoma by promoting oxidative stress and vascular dysfunction in the eye.

Causes retinal complications:

There are chahances of getting decreased capillary density and retinopathy due to persistent high uric acid levels in us. The retinal vessels in the eyes would get damaged due to oxidative stress and systemic inflammation. By this, our vision would get damaged. We could avoid retinal based complications by means of regular eye checkups and by managing our uric acid levels.

 How to protect our eye health by managing uric acid levels?

Uric acid levels can be managed by medications, limiting the intake of purine rich foods and intake of low purine foods like vegetables, whole grains etc. Uric acid could get flushed out from our body by drinking adequate water throughout the day. By this, crystal formation in the joints and ocular tissues would be avoided.